North-Eastern Hill University

Academic Identity

Orcid Id 0000-0002-9635-3024
Scopus Id 7102936916
Google Scholar Id T8HQWPwAAAAJ

Vidwan-ID : 161573

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Prof Nirmalendu Saha
Professor
North-Eastern Hill University

Publications 1986 - 2023

Publications

84

Journal Articles
6

Book Chapter
12

Projects
4
4

Citations / H-Index

1576 Citations

23 h-index

65 Citations

Google Scholar

Co-author Network

Expertise

Specialization in Fish Physiology and Biochemistry. Have been working for the last 35 years on different aspects of biochemical and physiological adaptation to various environmental stresses in Indian air-breathing catfishes with special reference to nitrogen, carbohydrate and protein metabolism, and on antioxidant strategies under different environmentally-induced oxidative stress along with the role of nitric oxide in adaptation to various environmental stresses.

Personal Information

Prof Nirmalendu Saha

Male

Biochemical Adaptation Lab., Department of Zoology, North-Eastern Hill University Umshing

Shillong, Meghalaya, India - 793022

Experience

1988 - Present

Professor

Department of Zoology

North-Eastern Hill University

Qualification

1987

Ph.D.

North-Eastern Hill University

Honours and Awards

2008

Fellowship

Zoological Society of India

2006

Fellowship

National Academy of Sciences

2005

Senior DAAD Fellowship

Govt. of Germany

2008

Fellowship

Zoological Society of India

2006

Fellowship

National Academy of Sciences

2005

Senior DAAD Fellowship

Govt. of Germany

2001

Visiting Scientist BAT II

SFB Germany

1997

Senior DAAD Fellowship

Govt. of Germany

1991

DAAD Fellowship

Govt. of Germany

1990

Young Scientist Award

Indian Science Congress Association

1987

Young Scientist Award

Ichthyological Scociety of India

1976

National Merit Scholarship

Govt. of India

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Doctoral Theses Guided

2021

Studies on environmentally-induced oxidative stress and the antioxidant strategies in air-breathing catfish, Clarias magur (Hamilton)

Dr. Rubaiya Hasan, North-Eastern Hill University

2020

Effects of zinc oxide nanoparticle and its bulk counterpart on oxidative stress in the air-breathing catfish Clarias batrachus (Bloch)

Dr. Debaprasad Koner, North-Eastern Hill University

2019

Effects of hyper-osmotic and hyper-ammonia stress on the induction of genes for ornithine-urea cycle, amino acid metabolism-related enzymes and nitric oxide synthase in the air-breathing catfish Clarias magur (Hamilton)

Dr. Suman Kumari, North-Eastern Hill University

2021

Studies on environmentally-induced oxidative stress and the antioxidant strategies in air-breathing catfish, Clarias magur (Hamilton)

Dr. Rubaiya Hasan, North-Eastern Hill University

2020

Effects of zinc oxide nanoparticle and its bulk counterpart on oxidative stress in the air-breathing catfish Clarias batrachus (Bloch)

Dr. Debaprasad Koner, North-Eastern Hill University

2019

Effects of hyper-osmotic and hyper-ammonia stress on the induction of genes for ornithine-urea cycle, amino acid metabolism-related enzymes and nitric oxide synthase in the air-breathing catfish Clarias magur (Hamilton)

Dr. Suman Kumari, North-Eastern Hill University

2018

Studies on the influence of hyper-ammonia and desiccation stresses on the expression of mRNAs for ornithine-urea cycle enzymes, enzyme proteins and mitogen-activated protein kinases in the air-breathing catfish, Heteropneustes fossilis (Bloch)

Dr. Priyanka Lal, North-Eastern Hill University

2017

Influence of hyper-ammonia and dehydration stresses on the expression of multiple glutamine synthetase genes heat shock protein 70 and mitogen-activated protein kinases in the mud eel, Monopterus cuchia

Dr. Hnunlalliani, North-Eastern Hill University

2017

Molecular characterization of the expression of genes of glutamine synthetases and ornithine-urea cycle enzymes and the involvement of mitogen activated protein kinases under hyper-ammonia stress in the air-breathing catfish, Clarias batrachus (Bloch)

Dr. Bodhisattwa Banerjee , North-Eastern Hill University

2014

Effect of osmotic stress on gluconeogenesis and mitogen activated protein kinases in the air-breathing catfish, Heteropneustes fossilis

Dr. Manas Das, North-Eastern Hill University

2013

Studies on tissue specific expression and induction of multiple glutamine synthetase genes under hyper-ammonia stress and ammonia-induced nitrotyrosination of glutamine synthetase in catfish Heteropneustes fossilis

Dr. Gitalee Bhuyan, North-Eastern Hill University

2012

Regulation and molecular characterization of different isoforms of nitric oxide synthase, nitric oxide production under environmental stress in the air-breathing catfish, Heteropneustes fossilis isoforms of nitric oxide synthase

Dr. Mahua G. Choudhury, North-Eastern Hill University

2011

Effect of osmotic, hyper-ammonia and desiccation stresses on gluconeogenesis in the air-breathing catfish, Clarias batrachus

Dr. Lucy M. Jyrwa, North-Eastern Hill University

2010

Study of adaptive strategies against ammonia toxicity in the amphibious mud eel Amphipnous cuchia

Dr. Jamesteword L. Khongsngi, North-Eastern Hill University

2007

Biochemical characterization of nitric oxide synthases, nitric oxide production and protein turnover during cell volume changes in the hepatocytes of air-breathing catfish, Clarias batrachus

Dr. Kuheli Biswas, North-Eastern Hill University

2006

Studies on nitrogen metabolism in the air-breathing batrachus during osmotic stress

Dr. Arundhati Bhattacharya, North-Eastern Hill University

2006

Purification and characterization of Glutamine synthase and its regulation under various environmental stresses in the air-breathing catfish Clarias batrachus

Dr. Shritapa Datta , North-Eastern Hill University

2005

Purification and characterization of the urea cycle related carbamyl phosphate synthetase(s) and expression of urea cycle enzymes in a ureogenic air-breathing catfish, Clarias batrachus during early life stages

Dr. Zaiba Y. Kharbuli, North-Eastern Hill University

2004

Antihelmintic efficacy of Flemingia vestita: An in vitro study on carbohydrate metabolism in the cestode Raillietina echinobothrida

Dr. Bidyadhar Das, North-Eastern Hill University

2003

Mechanism of cell volume changes on glucose metabolism and oxidative stress in perfused liver of freshwater air-breathing walking catfish Clarias batrachus

Dr. Carina Goswami, North-Eastern Hill University

2002

Amino acid metabolism in the freshwater air-breathing catfish Clarias batrachus under hyper-ammonia stress and osmotic stress

Dr. Supiya Dutta , North-Eastern Hill University

1996

Role of ureogenesis in a freshwater air-breathing catfish Clarias batrachus under environmental constraints

Dr. Lipika Das, North-Eastern Hill University

1995

Induction of urea cycle enzymes and characterization of arginase in a freshwater air-breathing teleost Heteropnesutes fossilis (Bloch)

Dr. Jacqueline Dkhar, North-Eastern Hill University

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Research Projects

To elucidate the roles of HIF and mTOR signaling pathways, and the autophagy in adaptation to hypoxia stress in air-breathing stinging catfish, Heteropneustes fossilis

Funding Agency : DST-SERB, New Delhi

Molecular adaptation during exposure to zinc oxide and titanium dioxide nanoparticles with special reference to oxidative stress, nitric oxide production, heat shock protein expression and induction of apoptosis in air-breathing catfish, Clarias batrachus

Funding Agency : DST-SERB, New Delhi

To elucidate the unique biochemical adaptational strategies that allow two air-breathing catfishes (Clarias batrachus and Heteropneustes fossilis) to survive in ammonia enriched toxic waste

Funding Agency : NASF-ICAR, New Delhi

Funding Agency : DST-SERB, New Delhi

Molecular adaptation during exposure to zinc oxide and titanium dioxide nanoparticles with special reference to oxidative stress, nitric oxide production, heat shock protein expression and induction of apoptosis in air-breathing catfish, Clarias batrachus

Funding Agency : DST-SERB, New Delhi

To elucidate the unique biochemical adaptational strategies that allow two air-breathing catfishes (Clarias batrachus and Heteropneustes fossilis) to survive in ammonia enriched toxic waste

Funding Agency : NASF-ICAR, New Delhi

Possible upregulation of ornithine-urea cycle genes and involvement of MAPKs to adapt under hyper-ammonia stress in air-breathing catfish, Clarias batrachus

Funding Agency : DST-SERB, New Delhi

Effects of high environmental ammonia on the expression of multiple glutamine synthetase genes, mitogen-activated protein kinases and Hsp70 in the air-breathing mud eel, Monopterus cuchia

Funding Agency : UGC, New Delhi

Molecular characterization in the expression of mRNAs for ornithine-urea cycle enzymes and enzyme proteins, multiple glutamine synthetase genes and signaling cascades under hyper-ammonia stress in the air-breathing walking catfish, Clarias batrachus

Funding Agency : DBT, New Delhi

Influence of hyper-ammonia stress on the expression of multiple glutamine synthetase genes, mRNAs for ornithine urea cycle enzymes and mitogen activated protein kinases in air-breathing catfish, Heteropneustes fossilis

Funding Agency : DST-SERB, New Delhi

Physiological significance of occurrence/expression and tissue distribution of nitric oxide synthases, production of nitric oxide under environmental constraints in the air-breathing catfish, Clarias batrachus.

Funding Agency : UGC, New Delhi

Physiological significance of occurrence/expression of different types of nitric oxide synthases and production of nitric oxide under environmental constraints and pathological conditions in catfish, Heteropneustes fossilis

Funding Agency : DST, New Delhi

Culture of carps and air-breathing fishes in hilly region and transfer of technology to rural population of Meghalaya

Funding Agency : DBT, New Delhi

Purification and characterization of carbamyl phosphate synthetase(s), and expression of urea cycle enzyme during early dvelopmental stages in an ambhibious potential ureogenic teleost, Clarias batrachus

Funding Agency : UGC, New Delhi

Adaptation to amino acid metabolism in freshwater air-breathing teleosts

Funding Agency : GTZ, Germany

Read Less

Academic Identity

Vidwan-ID : 161573

Prof Nirmalendu Saha

Publications 1986 - 2023

Publications

Journal Articles

Book Chapter

Projects

Citations / H-Index

Google Scholar

Co-author Network

Co-author - 146

Expertise

Personal Information

Prof Nirmalendu Saha

Experience

Professor

Qualification

Ph.D.

Honours and Awards

Fellowship

Fellowship

Senior DAAD Fellowship

Fellowship

Fellowship

Senior DAAD Fellowship

Visiting Scientist BAT II

Senior DAAD Fellowship

DAAD Fellowship

Young Scientist Award

Young Scientist Award

National Merit Scholarship

Doctoral Theses Guided

Studies on environmentally-induced oxidative stress and the antioxidant strategies in air-breathing catfish, Clarias magur (Hamilton)

Effects of zinc oxide nanoparticle and its bulk counterpart on oxidative stress in the air-breathing catfish Clarias batrachus (Bloch)

Effects of hyper-osmotic and hyper-ammonia stress on the induction of genes for ornithine-urea cycle, amino acid metabolism-related enzymes and nitric oxide synthase in the air-breathing catfish Clarias magur (Hamilton)

Studies on environmentally-induced oxidative stress and the antioxidant strategies in air-breathing catfish, Clarias magur (Hamilton)

Effects of zinc oxide nanoparticle and its bulk counterpart on oxidative stress in the air-breathing catfish Clarias batrachus (Bloch)

Effects of hyper-osmotic and hyper-ammonia stress on the induction of genes for ornithine-urea cycle, amino acid metabolism-related enzymes and nitric oxide synthase in the air-breathing catfish Clarias magur (Hamilton)

Studies on the influence of hyper-ammonia and desiccation stresses on the expression of mRNAs for ornithine-urea cycle enzymes, enzyme proteins and mitogen-activated protein kinases in the air-breathing catfish, Heteropneustes fossilis (Bloch)

Influence of hyper-ammonia and dehydration stresses on the expression of multiple glutamine synthetase genes heat shock protein 70 and mitogen-activated protein kinases in the mud eel, Monopterus cuchia

Molecular characterization of the expression of genes of glutamine synthetases and ornithine-urea cycle enzymes and the involvement of mitogen activated protein kinases under hyper-ammonia stress in the air-breathing catfish, Clarias batrachus (Bloch)

Effect of osmotic stress on gluconeogenesis and mitogen activated protein kinases in the air-breathing catfish, Heteropneustes fossilis

Studies on tissue specific expression and induction of multiple glutamine synthetase genes under hyper-ammonia stress and ammonia-induced nitrotyrosination of glutamine synthetase in catfish Heteropneustes fossilis

Regulation and molecular characterization of different isoforms of nitric oxide synthase, nitric oxide production under environmental stress in the air-breathing catfish, Heteropneustes fossilis isoforms of nitric oxide synthase

Effect of osmotic, hyper-ammonia and desiccation stresses on gluconeogenesis in the air-breathing catfish, Clarias batrachus

Study of adaptive strategies against ammonia toxicity in the amphibious mud eel Amphipnous cuchia

Biochemical characterization of nitric oxide synthases, nitric oxide production and protein turnover during cell volume changes in the hepatocytes of air-breathing catfish, Clarias batrachus

Studies on nitrogen metabolism in the air-breathing batrachus during osmotic stress

Purification and characterization of Glutamine synthase and its regulation under various environmental stresses in the air-breathing catfish Clarias batrachus

Purification and characterization of the urea cycle related carbamyl phosphate synthetase(s) and expression of urea cycle enzymes in a ureogenic air-breathing catfish, Clarias batrachus during early life stages

Antihelmintic efficacy of Flemingia vestita: An in vitro study on carbohydrate metabolism in the cestode Raillietina echinobothrida

Mechanism of cell volume changes on glucose metabolism and oxidative stress in perfused liver of freshwater air-breathing walking catfish Clarias batrachus

Amino acid metabolism in the freshwater air-breathing catfish Clarias batrachus under hyper-ammonia stress and osmotic stress

Role of ureogenesis in a freshwater air-breathing catfish Clarias batrachus under environmental constraints

Induction of urea cycle enzymes and characterization of arginase in a freshwater air-breathing teleost Heteropnesutes fossilis (Bloch)

Research Projects

To elucidate the roles of HIF and mTOR signaling pathways, and the autophagy in adaptation to hypoxia stress in air-breathing stinging catfish, Heteropneustes fossilis

Funding Agency : DST-SERB, New Delhi

Molecular adaptation during exposure to zinc oxide and titanium dioxide nanoparticles with special reference to oxidative stress, nitric oxide production, heat shock protein expression and induction of apoptosis in air-breathing catfish, Clarias batrachus

Funding Agency : DST-SERB, New Delhi

To elucidate the unique biochemical adaptational strategies that allow two air-breathing catfishes (Clarias batrachus and Heteropneustes fossilis) to survive in ammonia enriched toxic waste

Funding Agency : NASF-ICAR, New Delhi

To elucidate the roles of HIF and mTOR signaling pathways, and the autophagy in adaptation to hypoxia stress in air-breathing stinging catfish, Heteropneustes fossilis

Funding Agency : DST-SERB, New Delhi

Molecular adaptation during exposure to zinc oxide and titanium dioxide nanoparticles with special reference to oxidative stress, nitric oxide production, heat shock protein expression and induction of apoptosis in air-breathing catfish, Clarias batrachus

Funding Agency : DST-SERB, New Delhi

To elucidate the unique biochemical adaptational strategies that allow two air-breathing catfishes (Clarias batrachus and Heteropneustes fossilis) to survive in ammonia enriched toxic waste

Funding Agency : NASF-ICAR, New Delhi

Possible upregulation of ornithine-urea cycle genes and involvement of MAPKs to adapt under hyper-ammonia stress in air-breathing catfish, Clarias batrachus

Funding Agency : DST-SERB, New Delhi

Effects of high environmental ammonia on the expression of multiple glutamine synthetase genes, mitogen-activated protein kinases and Hsp70 in the air-breathing mud eel, Monopterus cuchia

Funding Agency : UGC, New Delhi

Molecular characterization in the expression of mRNAs for ornithine-urea cycle enzymes and enzyme proteins, multiple glutamine synthetase genes and signaling cascades under hyper-ammonia stress in the air-breathing walking catfish, Clarias batrachus

Funding Agency : DBT, New Delhi

Influence of hyper-ammonia stress on the expression of multiple glutamine synthetase genes, mRNAs for ornithine urea cycle enzymes and mitogen activated protein kinases in air-breathing catfish, Heteropneustes fossilis

Funding Agency : DST-SERB, New Delhi

Physiological significance of occurrence/expression and tissue distribution of nitric oxide synthases, production of nitric oxide under environmental constraints in the air-breathing catfish, Clarias batrachus.

Funding Agency : UGC, New Delhi

Physiological significance of occurrence/expression of different types of nitric oxide synthases and production of nitric oxide under environmental constraints and pathological conditions in catfish, Heteropneustes fossilis